Publications with the Minor Lab Go to top

1. Rubach P, Majorek KA, Gucwa M, Murzyn K, Wlodawer A, Minor W (2025)
   Advances in cryo-electron microscopy (cryoEM) for structure-based drug discovery.
   Expert Opin Drug Discov (): 1-14. [DOI:10.1080/17460441.2025.2450636] [Pub Med ID: 39789967]
   Google Scholar Times Cited: 0
2. Uychoco P, Majorek KA, Ives AN, Le VTB, Caro De Silva PL, Paurus VL, Attah IK, Lipton MS, Minor W, Kuhn ML (2025)
   Structural, functional, and regulatory evaluation of a cysteine post-translationally modified Gcn5-related N-acetyltransferase.
   Biochem Biophys Res Commun 748(): 151299. [DOI:10.1016/j.bbrc.2025.151299] [Pub Med ID: 39826527]
   Google Scholar Times Cited: 0
3. Majorek KA, Gucwa M, Murzyn K, Minor W (2024)
   Metal ions in biomedically relevant macromolecular structures.
   Front Chem 12(): 1426211. [DOI:10.3389/fchem.2024.1426211] [Pub Med ID: 39246722] [Pub Med Central ID: PMC11378719]
   WoS Times Cited: 1 ; Google Scholar Times Cited: 2
4. Baumgartner JT, Habeeb Mohammad TS, Czub MP, Majorek KA, Arolli X, Variot C, Anonick M, Minor W, Ballicora MA, Becker DP, Kuhn ML (2021)
   Gcn5-Related N-Acetyltransferases (GNATs) With a Catalytic Serine Residue Can Play Ping-Pong Too.
   Front Mol Biosci 8(): 646046. [DOI:10.3389/fmolb.2021.646046] [Pub Med ID: 33912589] [Pub Med Central ID: PMC8072286]
   WoS Times Cited: 16 ; Google Scholar Times Cited: 20
5. Shabalin IG, Czub MP, Majorek KA, Brzezinski D, Grabowski M, Cooper DR, Panasiuk M, Chruszcz M, Minor W (2020)
   Molecular determinants of vascular transport of dexamethasone in COVID-19 therapy.
   IUCrJ 7(Pt 6): 1048-1058. [DOI:10.1107/S2052252520012944] [Pub Med ID: 33063792] [Pub Med Central ID: PMC7553145]
   WoS Times Cited: 13 ; Google Scholar Times Cited: 15
6. Majorek KA, Zimmerman MD, Shabalin I, Zheng H, Minor W, Grabowski M (2020)
   Assessment of Crystallographic Structure Quality and Protein–Ligand Complex Structure Validation
   in Structural Biology in Drug Discovery: Methods, Techniques, and Practices (): 253-275. [DOI:10.1002/9781118681121.ch11]
   WoS Times Cited: 5 ; Google Scholar Times Cited: 4
7. Czub MP, Venkataramany BS, Majorek KA, Handing KB, Porebski PJ, Beeram SR, Suh K, Woolfork AG, Hage DS, Shabalin IG, Minor W (2019)
   Testosterone meets albumin - the molecular mechanism of sex hormone transport by serum albumins.
   Chem Sci 10(6): 1607-1618. [DOI:10.1039/c8sc04397c] [Pub Med ID: 30842823] [Pub Med Central ID: PMC6371759]
   WoS Times Cited: 41 ; Google Scholar Times Cited: 58
8. Czub MP, Zhang B, Chiarelli MP, Majorek KA, Joe L, Porebski PJ, Revilla A, Wu W, Becker DP, Minor W, Kuhn ML (2018)
   A Gcn5-Related N-Acetyltransferase (GNAT) Capable of Acetylating Polymyxin B and Colistin Antibiotics in Vitro.
   Biochemistry 57(51): 7011-7020. [DOI:10.1021/acs.biochem.8b00946] [Pub Med ID: 30499668] [Pub Med Central ID: PMC6474815]
   WoS Times Cited: 12 ; Google Scholar Times Cited: 20
9. Reidl C, Majorek KA, Dang J, Tran D, Jew K, Law M, Payne Y, Minor W, Becker DP, Kuhn ML (2017)
   Generating enzyme and radical-mediated bisubstrates as tools for investigating Gcn5-related N-acetyltransferases.
   FEBS Lett. 591(15): 2348-2361. [DOI:10.1002/1873-3468.12753] [Pub Med ID: 28703494] [Pub Med Central ID: PMC5578807]
   WoS Times Cited: 6 ; Google Scholar Times Cited: 8
10. Majorek KA, Osinski T, Tran DT, Revilla A, Anderson WF, Minor W, Kuhn ML (2017)
    Insight into the 3D structure and substrate specificity of previously uncharacterized GNAT superfamily acetyltransferases from pathogenic bacteria.
    Biochimica et biophysica acta. Proteins and proteomics 1865(1): 55-64. [DOI:10.1016/j.bbapap.2016.10.011] [Pub Med ID: 27783928] [Pub Med Central ID: PMC5127773]
    WoS Times Cited: 13 ; Google Scholar Times Cited: 17
11. Gasiorowska O, Handing KB, Majorek KA, Porebski PJ, Shabalin IG, Zasadzinska E, Cymborowski M, Minor W, Niedzialkowska E (2016)
    Protein purification and crystallization artifacts: The tale usually not told.
    Protein Sci 25(3): 720-33. [DOI:10.1002/pro.2861] [Pub Med ID: 26660914] [Pub Med Central ID: PMC4815408]
    WoS Times Cited: 39 ; Google Scholar Times Cited: 69
12. Handing KB, Shabalin IG, Szlachta K, Majorek KA, Minor W (2016)
    Crystal structure of equine serum albumin in complex with cetirizine reveals a novel drug binding site.
    Mol. Immunol. 71(): 143-151. [DOI:10.1016/j.molimm.2016.02.003] [Pub Med ID: 26896718] [Pub Med Central ID: PMC4800003]
    WoS Times Cited: 20 ; Google Scholar Times Cited: 24
13. Offermann LR, Osinski T, Pomés A, Majorek KA, Minor W, Vailes LD, Chapman MD, Chruszcz M, Glesner J (2015)
    Structural Analysis of Der p 1-Antibody Complexes and Comparison with Complexes of Proteins or Peptides with Monoclonal Antibodies.
    J. Immunol. 195(1): 307-16. [DOI:10.4049/jimmunol.1402199] [Pub Med ID: 26026055] [Pub Med Central ID: PMC4475478]
    WoS Times Cited: 27 ; Google Scholar Times Cited: 34
14. Majorek KA, Minor W, Chruszcz M, Anderson WF, Kuhn ML (2014)
    Double trouble-Buffer selection and His-tag presence may be responsible for nonreproducibility of biomedical experiments.
    Protein Sci 23(10): 1359-68. [DOI:10.1002/pro.2520] [Pub Med ID: 25044180] [Pub Med Central ID: PMC4286991]
    WoS Times Cited: 89 ; Google Scholar Times Cited: 141
15. Majorek KA, Chruszcz M, Maleki SJ, Offermann LR, McBride JK, Hurlburt BK (2013)
    Structure and function of the peanut panallergen Ara h 8.
    J. Biol. Chem. 288(52): 36890-901. [DOI:10.1074/jbc.M113.517797] [Pub Med ID: 24253038] [Pub Med Central ID: PMC3873548]
    WoS Times Cited: 41 ; Google Scholar Times Cited: 83
16. Osinski T, Majorek KA, Font J, Minor W, Thalassinos K, Giangrieco I, Ciardiello MA, Breiteneder H, Chruszcz M (2013)
    Structural and bioinformatic analysis of the kiwifruit allergen Act d 11, a member of the family of ripening-related proteins.
    Mol. Immunol. 56(4): 794-803. [DOI:10.1016/j.molimm.2013.07.004] [Pub Med ID: 23969108] [Pub Med Central ID: PMC3783527]
    WoS Times Cited: 39 ; Google Scholar Times Cited: 53
17. Mikolajczak K, Majorek KA, Porebski PJ, Minor W, Mank N, Chruszcz M (2013)
    Serum albumins-unusual allergens.
    Biochim. Biophys. Acta 1830(12): 5375-81. [DOI:10.1016/j.bbagen.2013.06.016] [Pub Med ID: 23811341] [Pub Med Central ID: PMC4419372]
    WoS Times Cited: 94 ; Google Scholar Times Cited: 141
18. Majorek KA, Minor W, Chruszcz M, Anderson WF, Kuhn ML (2013)
    Structural, functional, and inhibition studies of a Gcn5-related N-acetyltransferase (GNAT) superfamily protein PA4794: a new C-terminal lysine protein acetyltransferase from pseudomonas aeruginosa.
    J. Biol. Chem. 288(42): 30223-35. [DOI:10.1074/jbc.M113.501353] [Pub Med ID: 24003232] [Pub Med Central ID: PMC3798489]
    WoS Times Cited: 35 ; Google Scholar Times Cited: 40
19. Majorek KA, Minor W, Anderson WF, Kuhn ML (2013)
    Broad-substrate screen as a tool to identify substrates for bacterial Gcn5-related N-acetyltransferases with unknown substrate specificity.
    Protein Sci 22(2): 222-30. [DOI:10.1002/pro.2199] [Pub Med ID: 23184347] [Pub Med Central ID: PMC3588918]
    WoS Times Cited: 48 ; Google Scholar Times Cited: 66
20. Knapik AA, Petkowski JJ, Cymborowski MT, Cooper DR, Majorek KA, Chruszcz M, Minor W, Otwinowski Z, Krajewska WM (2012)
    A multi-faceted analysis of RutD reveals a novel family of α/β hydrolases.
    Proteins 80(10): 2359-68. [DOI:10.1002/prot.24122] [Pub Med ID: 22641504] [Pub Med Central ID: PMC3459670]
    WoS Times Cited: 8 ; Google Scholar Times Cited: 10
21. Majorek KA, Porebski PJ, Dayal A, Zimmerman MD, Jablonska K, Chruszcz M, Minor W, Stewart AJ (2012)
    Structural and immunologic characterization of bovine, horse, and rabbit serum albumins.
    Mol. Immunol. 52(3-4): 174-82. [DOI:10.1016/j.molimm.2012.05.011] [Pub Med ID: 22677715] [Pub Med Central ID: PMC3401331]
    WoS Times Cited: 769 ; Google Scholar Times Cited: 1,122
22. Chruszcz M, Osinski T, Chapman MD, Solberg R, Demas M, Porebski PJ, Majorek KA, Pomés A, Minor W (2012)
    Alternaria alternata allergen Alt a 1: a unique β-barrel protein dimer found exclusively in fungi.
    J. Allergy Clin. Immunol. 130(1): 241-7.e9. [DOI:10.1016/j.jaci.2012.03.047] [Pub Med ID: 22664167] [Pub Med Central ID: PMC3391610]
    WoS Times Cited: 79 ; Google Scholar Times Cited: 128
23. Chruszcz M, Pomés A, Osinski T, Porebski PJ, Majorek KA, Heymann PW, Platts-Mills TA, Minor W, Vailes LD, Glesner J, Chapman MD (2012)
    Molecular determinants for antibody binding on group 1 house dust mite allergens.
    J. Biol. Chem. 287(10): 7388-98. [DOI:10.1074/jbc.M111.311159] [Pub Med ID: 22210776] [Pub Med Central ID: PMC3293536]
    WoS Times Cited: 76 ; Google Scholar Times Cited: 102
24. Chruszcz M, Majorek KA, Demas M, Solberg R, Mattison CP, Minor W, Ruan S, Bublin M, Breiteneder H, Maleki SJ, Hurlburt BK, Mattisohn CP (2011)
    Structural and immunologic characterization of Ara h 1, a major peanut allergen.
    J. Biol. Chem. 286(45): 39318-27. [DOI:10.1074/jbc.M111.270132] [Pub Med ID: 21917921] [Pub Med Central ID: PMC3234756]
    WoS Times Cited: 80 ; Google Scholar Times Cited: 121

Structures with the Minor Lab Go to top