• Training Period: 2016-2017, MSc 2017-present, PhD
  • Prior Institution: Jagiellonian University
  • Prior Degree: B.Sc. (2015)
  • Project Title: Albumins
  • Current Position: Post Doctoral, Paul Scherrer Institute, Switzerland

Education:
  • Ph.D. Program in Biomedical Sciences (BIMS), University of Virginia, Charlottesville, USA, 2017 - 2020
  • Visiting Graduate Student at the University of Virginia, Charlottesville, USA, 2016 - 2017
  • M.Sc. in Chemistry (Specialization - Biological Chemistry), Jagiellonian University, Krakow, Poland, 2017
  • B.Sc. in Chemistry (Inter-Faculty Studies in Mathematics and Natural Sciences), Jagiellonian University, Krakow, Poland 2015
Research Interest:
  • Protein crystallography
  • Structural biology
  • Biophysics
Projects:
  • Studies of drug, hormone, and metal ion transport by serum albumin
  • Structural and biochemical characterization of the PA3944 acetyltransferase from Pseudomonas aeruginosa
CV:
  • Molecular Pharmacology Highlighted Trainee Author (December 2020)
  • Robert R. Wagner Fellowship (2020)
  • Travel Award from the Biophysical Society to participate in the Biophysical Society 64th Annual Meeting in San Diego, CA, USA (2020)
  • Scholarship of the Polish Minister of Science and Higher Education for outstanding achievements (2015)
  • Recipient of the DuPont Company Award in the "Golden Medal of Chemistry" contest for the best bachelor or engineering thesis organized by the Polish Academy of Sciences and DuPont Company (2015)

Publications with the Minor Lab

  1. Baumgartner JT, Habeeb Mohammad TS, Czub MP, Majorek KA, Arolli X, Variot C, Anonick M, Minor W, Ballicora MA, Becker DP, Kuhn ML (2021)
    Gcn5-Related
    Front Mol Biosci 8: 646046. [DOI:10.3389/fmolb.2021.646046] [Pub Med ID: 33912589] [Pub Med Central ID: PMC8072286] Times cited: 1
  2. Cooper DR, Grabowski M, Zimmerman MD, Porebski PJ, Shabalin IG, Woinska M, Domagalski MJ, Zheng H, Sroka P, Cymborowski M, Czub MP, Niedzialkowska E, Venkataramany BS, Osinski T, Fratczak Z, Bajor J, Gonera J, MacLean E, Wojciechowska K, Konina K, Wajerowicz W, Chruszcz M, Minor W (2020)
    State-of-the-Art Data Management: Improving the Reproducibility, Consistency, and Traceability of Structural Biology and in Vitro Biochemical Experiments.
    Methods Mol Biol 2199: 209-236. [DOI:10.1007/978-1-0716-0892-0_13] [Pub Med ID: 33125653] [Pub Med Central ID: PMC8019398] Times cited: 3
  3. Czub MP, Boulton AM, Rastelli EJ, Tasker NR, Maskrey TS, Blanco IK, McQueeney KE, Bushweller JH, Minor W, Wipf P, Sharlow ER, Lazo JS (2020)
    Structure of the Complex of an Iminopyridinedione Protein Tyrosine Phosphatase 4A3 Phosphatase Inhibitor with Human Serum Albumin.
    Mol Pharmacol 98: 648-657. [DOI:10.1124/molpharm.120.000131] [Pub Med ID: 32978326] [Pub Med Central ID: PMC7658597] Times cited: 4
  4. Shabalin IG, Czub MP, Majorek KA, Brzezinski D, Grabowski M, Cooper DR, Panasiuk M, Chruszcz M, Minor W (2020)
    Molecular determinants of vascular transport of dexamethasone in COVID-19 therapy.
    IUCrJ [DOI:10.1107/S2052252520012944] [Pub Med ID: 33063792] [Pub Med Central ID: PMC7553145] Times cited: 6
  5. Czub MP, Handing KB, Venkataramany BS, Cooper DR, Shabalin IG, Minor W (2020)
    Albumin-Based Transport of Nonsteroidal Anti-Inflammatory Drugs in Mammalian Blood Plasma.
    J Med Chem 63: 6847-6862. [DOI:10.1021/acs.jmedchem.0c00225] [Pub Med ID: 32469516] [Pub Med Central ID: PMC7902233] Times cited: 10
  6. Czub MP, Venkataramany BS, Majorek KA, Handing KB, Porebski PJ, Beeram SR, Suh K, Woolfork AG, Hage DS, Shabalin IG, Minor W (2019)
    Testosterone meets albumin - the molecular mechanism of sex hormone transport by serum albumins.
    Chem Sci 10: 1607-1618. [DOI:10.1039/c8sc04397c] [Pub Med ID: 30842823] [Pub Med Central ID: PMC6371759] Times cited: 17
  7. Czub MP, Zhang B, Chiarelli MP, Majorek KA, Joe L, Porebski PJ, Revilla A, Wu W, Becker DP, Minor W, Kuhn ML (2018)
    A Gcn5-Related N-Acetyltransferase (GNAT) Capable of Acetylating Polymyxin B and Colistin Antibiotics in Vitro.
    Biochemistry 57: 7011-7020. [DOI:10.1021/acs.biochem.8b00946] [Pub Med ID: 30499668] [Pub Med Central ID: PMC6474815] Times cited: 8
  8. Niedzialkowska E, Mrugała B, Rugor A, Czub MP, Skotnicka A, Cotelesage JJH, George GN, Szaleniec M, Minor W, Lewiński K (2017)
    Optimization of overexpression of a chaperone protein of steroid C25 dehydrogenase for biochemical and biophysical characterization.
    Protein Expr. Purif. 134: 47-62. [DOI:10.1016/j.pep.2017.03.019] [Pub Med ID: 28343996] [Pub Med Central ID: PMC5535313] Times cited: 4