• e-mail: Chruszcz@mailbox.sc.edu
  • Co-author of 93 publications with the Minor Lab  (cited 4,102 times) [show]
  • Co-author of 218 structures with the Minor Lab [show]
  • Relative Citation Ratio (RCR): 119.82

  • Training Period: 1996, Visiting Student<br/>2002-08, Postdoc<br/>2008-11, Instructor<br/>2011-12, Research Assistant Professor
  • Prior Institution: Jagiellonian University, Poland
  • Prior Degree: PhD (2002)
  • Project Title: Structural Biology, Allergens
  • Current Position: Associate Professor, University of South Carolina, USA

Publications with the Minor Lab

  1. Hou J, Zheng H, Tzou WS, Cooper DR, Chruszcz M, Chordia MD, Kwon K, Grabowski M, Minor W (2018)
    Differences in substrate specificity of V. cholerae FabH enzymes suggest new approaches for the development of novel antibiotics and biofuels.
    FEBS J. 285: 2900-2921. [DOI:10.1111/febs.14588] [Pub Med ID: 29917313] [Pub Med Central ID: PMC6105497] Times cited: 1
  2. Miłaczewska A, Kot E, Amaya JA, Makris TM, Zając M, Korecki J, Chumakov A, Trzewik B, Kędracka-Krok S, Minor W, Chruszcz M, Borowski T (2018)
    On the Structure and Reaction Mechanism of Human Acireductone Dioxygenase.
    Chemistry 24: 5225-5237. [DOI:10.1002/chem.201704617] [Pub Med ID: 29193386] Times cited: 4
  3. Glesner J, Vailes LD, Schlachter C, Mank N, Minor W, Osinski T, Chruszcz M, Chapman MD, Pomés A (2017)
    Antigenic Determinants of Der p 1: Specificity and Cross-Reactivity Associated with IgE Antibody Recognition.
    J. Immunol. 198: 1334-1344. [DOI:10.4049/jimmunol.1600072] [Pub Med ID: 28039303] [Pub Med Central ID: PMC5263215] Times cited: 5
  4. Handing KB, Shabalin IG, Kassaar O, Khazaipoul S, Blindauer CA, Stewart AJ, Chruszcz M, Minor W (2016)
    Circulatory zinc transport is controlled by distinct interdomain sites on mammalian albumins.
    Chem Sci 7: 6635-6648. [DOI:10.1039/c6sc02267g] [Pub Med ID: 28567254] [Pub Med Central ID: PMC5450522] Times cited: 21
  5. Hou J, Zheng H, Chruszcz M, Zimmerman MD, Shumilin IA, Osinski T, Demas M, Grimshaw S, Minor W (2015)
    Dissecting the Structural Elements for the Activation of β-Ketoacyl-(Acyl Carrier Protein) Reductase from Vibrio cholerae.
    J. Bacteriol. 198: 463-76. [DOI:10.1128/JB.00360-15] [Pub Med ID: 26553852] [Pub Med Central ID: PMC4719456] Times cited: 6
  6. Pomés A, Chruszcz M, Gustchina A, Minor W, Mueller GA, Pedersen LC, Wlodawer A, Chapman MD (2015)
    100 Years later: Celebrating the contributions of x-ray crystallography to allergy and clinical immunology.
    J. Allergy Clin. Immunol. 136: 29-37.e10. [DOI:10.1016/j.jaci.2015.05.016] [Pub Med ID: 26145985] [Pub Med Central ID: PMC4502579] Times cited: 12
  7. Osinski T, Pomés A, Majorek KA, Glesner J, Offermann LR, Vailes LD, Chapman MD, Minor W, Chruszcz M (2015)
    Structural Analysis of Der p 1-Antibody Complexes and Comparison with Complexes of Proteins or Peptides with Monoclonal Antibodies.
    J. Immunol. 195: 307-16. [DOI:10.4049/jimmunol.1402199] [Pub Med ID: 26026055] [Pub Med Central ID: PMC4475478] Times cited: 12
  8. Filippova EV, Tkaczuk KL, Chruszcz M, Xu X, Savchenko A, Edwards A, Minor W (2014)
    Structural characterization of the putative ABC-type 2 transporter from Thermotoga maritima MSB8.
    J. Struct. Funct. Genomics 15: 215-22. [DOI:10.1007/s10969-014-9189-7] [Pub Med ID: 25306867] [Pub Med Central ID: PMC4239177]
  9. Majorek KA, Kuhn ML, Chruszcz M, Anderson WF, Minor W (2014)
    Double trouble-Buffer selection and His-tag presence may be responsible for nonreproducibility of biomedical experiments.
    Protein Sci. 23: 1359-68. [DOI:10.1002/pro.2520] [Pub Med ID: 25044180] [Pub Med Central ID: PMC4286991] Times cited: 35
  10. Offermann LR, Chan SL, Osinski T, Tan YW, Chew FT, Sivaraman J, Mok YK, Minor W, Chruszcz M (2014)
    The major cockroach allergen Bla g 4 binds tyramine and octopamine.
    Mol. Immunol. 60: 86-94. [DOI:10.1016/j.molimm.2014.03.016] [Pub Med ID: 24769496] [Pub Med Central ID: PMC4097008] Times cited: 7
  11. Bajor J, Tkaczuk KL, Chruszcz M, Chapman H, Kagan O, Savchenko A, Minor W (2014)
    The crystal structure of pyrimidine/thiamin biosynthesis precursor-like domain-containing protein CAE31940 from proteobacterium Bordetella bronchiseptica RB50, and evolutionary insight into the NMT1/THI5 family.
    J. Struct. Funct. Genomics 15: 73-81. [DOI:10.1007/s10969-014-9180-3] [Pub Med ID: 24908050] [Pub Med Central ID: PMC4115252]
  12. Rashin AA, Domagalski MJ, Zimmermann MT, Minor W, Chruszcz M, Jernigan RL (2014)
    Factors correlating with significant differences between X-ray structures of myoglobin.
    Acta Crystallogr D Biol Crystallogr. 70: 481-91. [DOI:10.1107/S1399004713028812] [Pub Med ID: 24531482] [Pub Med Central ID: PMC3940193] Times cited: 5
  13. Zimmerman MD, Grabowski M, Domagalski MJ, Maclean EM, Chruszcz M, Minor W (2014)
    Data management in the modern structural biology and biomedical research environment.
    Methods Mol. Biol. 1140: 1-25. [DOI:10.1007/978-1-4939-0354-2_1] [Pub Med ID: 24590705] [Pub Med Central ID: PMC4086192] Times cited: 18
  14. Zheng H, Chordia MD, Cooper DR, Chruszcz M, Müller P, Sheldrick GM, Minor W (2014)
    Validation of metal-binding sites in macromolecular structures with the CheckMyMetal web server.
    Nat Protoc 9: 156-70. [DOI:10.1038/nprot.2013.172] [Pub Med ID: 24356774] [Pub Med Central ID: PMC4410975] Times cited: 148
  15. Hurlburt BK, Offermann LR, McBride JK, Majorek KA, Maleki SJ, Chruszcz M (2013)
    Structure and function of the peanut panallergen Ara h 8.
    J. Biol. Chem. 288: 36890-901. [DOI:10.1074/jbc.M113.517797] [Pub Med ID: 24253038] [Pub Med Central ID: PMC3873548] Times cited: 25
  16. Chruszcz M, Ciardiello MA, Osinski T, Majorek KA, Giangrieco I, Font J, Breiteneder H, Thalassinos K, Minor W (2013)
    Structural and bioinformatic analysis of the kiwifruit allergen Act d 11, a member of the family of ripening-related proteins.
    Mol. Immunol. 56: 794-803. [DOI:10.1016/j.molimm.2013.07.004] [Pub Med ID: 23969108] [Pub Med Central ID: PMC3783527] Times cited: 17
  17. Chruszcz M, Mikolajczak K, Mank N, Majorek KA, Porebski PJ, Minor W (2013)
    Serum albumins-unusual allergens.
    Biochim. Biophys. Acta 1830: 5375-81. [DOI:10.1016/j.bbagen.2013.06.016] [Pub Med ID: 23811341] [Pub Med Central ID: PMC4419372] Times cited: 49
  18. Majorek KA, Kuhn ML, Chruszcz M, Anderson WF, Minor W (2013)
    Structural, functional, and inhibition studies of a Gcn5-related N-acetyltransferase (GNAT) superfamily protein PA4794: a new C-terminal lysine protein acetyltransferase from pseudomonas aeruginosa.
    J. Biol. Chem. 288: 30223-35. [DOI:10.1074/jbc.M113.501353] [Pub Med ID: 24003232] [Pub Med Central ID: PMC3798489] Times cited: 23
  19. Luo HB, Knapik AA, Petkowski JJ, Demas M, Shumilin IA, Zheng H, Chruszcz M, Minor W (2013)
    Biophysical analysis of the putative acetyltransferase SACOL2570 from methicillin-resistant Staphylococcus aureus.
    J. Struct. Funct. Genomics 14: 97-108. [DOI:10.1007/s10969-013-9158-6] [Pub Med ID: 23963951] [Pub Med Central ID: PMC3923901] Times cited: 2
  20. Domagalski MJ, Tkaczuk KL, Chruszcz M, Skarina T, Onopriyenko O, Cymborowski M, Grabowski M, Savchenko A, Minor W (2013)
    Structure of isochorismate synthase DhbC from Bacillus anthracis.
    Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 69: 956-61. [DOI:10.1107/S1744309113021246] [Pub Med ID: 23989140] [Pub Med Central ID: PMC3758140]
  21. Tkaczuk KL, A Shumilin I, Chruszcz M, Evdokimova E, Savchenko A, Minor W (2013)
    Structural and functional insight into the universal stress protein family.
    Evol Appl 6: 434-49. [DOI:10.1111/eva.12057] [Pub Med ID: 23745136] [Pub Med Central ID: PMC3673472] Times cited: 42
  22. Trillo-Muyo S, Jasilionis A, Domagalski MJ, Chruszcz M, Minor W, Kuisiene N, Arolas JL, Solà M, Gomis-Rüth FX (2013)
    Ultratight crystal packing of a 10 kDa protein.
    Acta Crystallogr D Biol Crystallogr. 69: 464-70. [DOI:10.1107/S0907444912050135] [Pub Med ID: 23519421] [Pub Med Central ID: PMC4048058] Times cited: 9
  23. Knapik AA, Petkowski JJ, Otwinowski Z, Cymborowski MT, Cooper DR, Chruszcz M, Krajewska WM, Minor W (2012)
    Structure of Escherichia coli RutC, a member of the YjgF family and putative aminoacrylate peracid reductase of the rut operon.
    Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 68: 1294-9. [DOI:10.1107/S1744309112041796] [Pub Med ID: 23143235] [Pub Med Central ID: PMC3515367] Times cited: 6
  24. Majorek KA, Porebski PJ, Dayal A, Zimmerman MD, Jablonska K, Stewart AJ, Chruszcz M, Minor W (2012)
    Structural and immunologic characterization of bovine, horse, and rabbit serum albumins.
    Mol. Immunol. 52: 174-82. [DOI:10.1016/j.molimm.2012.05.011] [Pub Med ID: 22677715] [Pub Med Central ID: PMC3401331] Times cited: 368
  25. Knapik AA, Petkowski JJ, Otwinowski Z, Cymborowski MT, Cooper DR, Majorek KA, Chruszcz M, Krajewska WM, Minor W (2012)
    A multi-faceted analysis of RutD reveals a novel family of α/β hydrolases.
    Proteins 80: 2359-68. [DOI:10.1002/prot.24122] [Pub Med ID: 22641504] [Pub Med Central ID: PMC3459670] Times cited: 4
  26. Shabalin IG, Porebski PJ, Cooper DR, Grabowski M, Onopriyenko O, Grimshaw S, Savchenko A, Chruszcz M, Minor W (2012)
    Structure of anabolic ornithine carbamoyltransferase from Campylobacter jejuni at 2.7 Å resolution.
    Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 68: 1018-24. [DOI:10.1107/S1744309112031259] [Pub Med ID: 22949186] [Pub Med Central ID: PMC3433189] Times cited: 4
  27. Chruszcz M, Chapman MD, Osinski T, Solberg R, Demas M, Porebski PJ, Majorek KA, Pomés A, Minor W (2012)
    Alternaria alternata allergen Alt a 1: a unique β-barrel protein dimer found exclusively in fungi.
    J. Allergy Clin. Immunol. 130: 241-7.e9. [DOI:10.1016/j.jaci.2012.03.047] [Pub Med ID: 22664167] [Pub Med Central ID: PMC3391610] Times cited: 40
  28. Hou J, Wojciechowska K, Zheng H, Chruszcz M, Cooper DR, Cymborowski M, Skarina T, Gordon E, Luo H, Savchenko A, Minor W (2012)
    Structure of a short-chain dehydrogenase/reductase from Bacillus anthracis.
    Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 68: 632-7. [DOI:10.1107/S1744309112017939] [Pub Med ID: 22684058] [Pub Med Central ID: PMC3370898] Times cited: 2
  29. Davis GC, Kong Y, Paige M, Li Z, Merrick EC, Hansen T, Suy S, Wang K, Dakshanamurthy S, Cordova A, McManus OB, Williams BS, Chruszcz M, Minor W, Patel MK, Brown ML (2012)
    Asymmetric synthesis and evaluation of a hydroxyphenylamide voltage-gated sodium channel blocker in human prostate cancer xenografts.
    Bioorg. Med. Chem. 20: 2180-8. [DOI:10.1016/j.bmc.2011.08.061] [Pub Med ID: 22364743] [Pub Med Central ID: PMC4111568] Times cited: 12
  30. Chruszcz M, Pomés A, Glesner J, Vailes LD, Osinski T, Porebski PJ, Majorek KA, Heymann PW, Platts-Mills TA, Minor W, Chapman MD (2012)
    Molecular determinants for antibody binding on group 1 house dust mite allergens.
    J. Biol. Chem. 287: 7388-98. [DOI:10.1074/jbc.M111.311159] [Pub Med ID: 22210776] [Pub Med Central ID: PMC3293536] Times cited: 55
  31. Porebski PJ, Klimecka M, Chruszcz M, Nicholls RA, Murzyn K, Cuff ME, Xu X, Cymborowski M, Murshudov GN, Savchenko A, Edwards A, Minor W (2012)
    Structural characterization of Helicobacter pylori dethiobiotin synthetase reveals differences between family members.
    FEBS J. 279: 1093-105. [DOI:10.1111/j.1742-4658.2012.08506.x] [Pub Med ID: 22284390] [Pub Med Central ID: PMC3392494] Times cited: 7
  32. Zheng H, Filippova EV, Tkaczuk KL, Dworzynski P, Chruszcz M, Porebski PJ, Wawrzak Z, Onopriyenko O, Kudritska M, Grimshaw S, Savchenko A, Anderson WF, Minor W (2012)
    Crystal structures of putative phosphoglycerate kinases from B. anthracis and C. jejuni.
    J. Struct. Funct. Genomics 13: 15-26. [DOI:10.1007/s10969-012-9131-9] [Pub Med ID: 22403005] [Pub Med Central ID: PMC4485498] Times cited: 3
  33. Goral AM, Tkaczuk KL, Chruszcz M, Kagan O, Savchenko A, Minor W (2012)
    Crystal structure of a putative isochorismatase hydrolase from Oleispira antarctica.
    J. Struct. Funct. Genomics 13: 27-36. [DOI:10.1007/s10969-012-9127-5] [Pub Med ID: 22350524] [Pub Med Central ID: PMC3328404] Times cited: 11
  34. Barber-Rotenberg JS, Selvanathan SP, Kong Y, Erkizan HV, Snyder TM, Hong SP, Kobs CL, South NL, Summer S, Monroe PJ, Chruszcz M, Dobrev V, Tosso PN, Scher LJ, Minor W, Brown ML, Metallo SJ, Üren A, Toretsky JA (2012)
    Single enantiomer of YK-4-279 demonstrates specificity in targeting the oncogene EWS-FLI1.
    Oncotarget 3: 172-82. [DOI:10.18632/oncotarget.454] [Pub Med ID: 22383402] [Pub Med Central ID: PMC3326647] Times cited: 46
    F1000 Recommended Publication
  35. Chruszcz M, Maleki SJ, Majorek KA, Demas M, Bublin M, Solberg R, Hurlburt BK, Ruan S, Mattison CP, Mattisohn CP, Breiteneder H, Minor W (2011)
    Structural and immunologic characterization of Ara h 1, a major peanut allergen.
    J. Biol. Chem. 286: 39318-27. [DOI:10.1074/jbc.M111.270132] [Pub Med ID: 21917921] [Pub Med Central ID: PMC3234756] Times cited: 57
  36. Murai MJ, Chruszcz M, Reddy G, Grembecka J, Cierpicki T (2011)
    Crystal structure of menin reveals binding site for mixed lineage leukemia (MLL) protein.
    J. Biol. Chem. 286: 31742-8. [DOI:10.1074/jbc.M111.258186] [Pub Med ID: 21757704] [Pub Med Central ID: PMC3173070] Times cited: 51
  37. Filippova EV, Chruszcz M, Cymborowski M, Gu J, Savchenko A, Edwards A, Minor W (2011)
    Crystal structure of a putative transcriptional regulator SCO0520 from Streptomyces coelicolor A3(2) reveals an unusual dimer among TetR family proteins.
    J. Struct. Funct. Genomics 12: 149-57. [DOI:10.1007/s10969-011-9112-4] [Pub Med ID: 21625866] [Pub Med Central ID: PMC4413006] Times cited: 4
  38. Cooper DR, Porebski PJ, Chruszcz M, Minor W (2011)
    X-ray crystallography: Assessment and validation of protein-small molecule complexes for drug discovery.
    Expert Opin Drug Discov 6: 771-782. [DOI:10.1517/17460441.2011.585154] [Pub Med ID: 21779303] [Pub Med Central ID: PMC3138648] Times cited: 33
  39. Klimecka MM, Chruszcz M, Font J, Skarina T, Shumilin I, Onopryienko O, Porebski PJ, Cymborowski M, Zimmerman MD, Hasseman J, Glomski IJ, Lebioda L, Savchenko A, Edwards A, Minor W (2011)
    Structural analysis of a putative aminoglycoside N-acetyltransferase from Bacillus anthracis.
    J. Mol. Biol. 410: 411-23. [DOI:10.1016/j.jmb.2011.04.076] [Pub Med ID: 21601576] [Pub Med Central ID: PMC3131501] Times cited: 9
  40. Mendez DL, Kim D, Chruszcz M, Stephens GE, Minor W, Khorasanizadeh S, Elgin SC (2011)
    The HP1a disordered C terminus and chromo shadow domain cooperate to select target peptide partners.
    Chembiochem 12: 1084-96. [DOI:10.1002/cbic.201000598] [Pub Med ID: 21472955] [Pub Med Central ID: PMC3154745] Times cited: 37
  41. Chruszcz M, Domagalski M, Osinski T, Wlodawer A, Minor W (2010)
    Unmet challenges of structural genomics.
    Curr. Opin. Struct. Biol. 20: 587-97. [DOI:10.1016/j.sbi.2010.08.001] [Pub Med ID: 20810277] [Pub Med Central ID: PMC3017768] Times cited: 29
  42. Cymborowski M, Klimecka M, Chruszcz M, Zimmerman MD, Shumilin IA, Borek D, Lazarski K, Joachimiak A, Otwinowski Z, Anderson W, Minor W (2010)
    To automate or not to automate: this is the question.
    J. Struct. Funct. Genomics 11: 211-21. [DOI:10.1007/s10969-010-9092-9] [Pub Med ID: 20526815] [Pub Med Central ID: PMC2921494] Times cited: 19
  43. Sledź P, Kamiński R, Chruszcz M, Zimmerman MD, Minor W, Woźniak K (2010)
    An experimental charge density of HEPES.
    Acta Crystallogr., B 66: 482-92. [DOI:10.1107/S0108768110023025] [Pub Med ID: 20631430] Times cited: 11
  44. Sledz P, Zheng H, Murzyn K, Chruszcz M, Zimmerman MD, Chordia MD, Joachimiak A, Minor W (2010)
    New surface contacts formed upon reductive lysine methylation: improving the probability of protein crystallization.
    Protein Sci. 19: 1395-404. [DOI:10.1002/pro.420] [Pub Med ID: 20506323] [Pub Med Central ID: PMC2974831] Times cited: 24
  45. Luo HB, Zheng H, Zimmerman MD, Chruszcz M, Skarina T, Egorova O, Savchenko A, Edwards AM, Minor W (2010)
    Crystal structure and molecular modeling study of N-carbamoylsarcosine amidase Ta0454 from Thermoplasma acidophilum.
    J. Struct. Biol. 169: 304-11. [DOI:10.1016/j.jsb.2009.11.008] [Pub Med ID: 19932181] [Pub Med Central ID: PMC2830209] Times cited: 13
  46. Cabello R, Chruszcz M, Minor W (2009)
    2,4-Dichloro-benzaldehyde.
    Acta Crystallogr Sect E Struct Rep Online 66: o243. [DOI:10.1107/S160053680905435X] [Pub Med ID: 21580124] [Pub Med Central ID: PMC2980260] Times cited: 1
  47. Koclega KD, Chruszcz M, Zimmerman MD, Bujacz G, Minor W (2009)
    'Hot' macromolecular crystals.
    Cryst Growth Des 10: 580. [DOI:10.1021/cg900971h] [Pub Med ID: 20161694] [Pub Med Central ID: PMC2809425] Times cited: 5
  48. Sledz P, Minor T, Chruszcz M (2009)
    Redetermination of 2-[4-(2-hydroxy-ethyl)piperazin-1-ium-1-yl]ethanesul-fonate at 100 K.
    Acta Crystallogr Sect E Struct Rep Online 65: o3027-8. [DOI:10.1107/S1600536809042512] [Pub Med ID: 21578764] [Pub Med Central ID: PMC2971979] Times cited: 5
  49. Wang S, Kirillova O, Chruszcz M, Gront D, Zimmerman MD, Cymborowski MT, Shumilin IA, Skarina T, Gorodichtchenskaia E, Savchenko A, Edwards AM, Minor W (2009)
    The crystal structure of the AF2331 protein from Archaeoglobus fulgidus DSM 4304 forms an unusual interdigitated dimer with a new type of alpha + beta fold.
    Protein Sci. 18: 2410-9. [DOI:10.1002/pro.251] [Pub Med ID: 19768810] [Pub Med Central ID: PMC2788295] Times cited: 2
  50. Grabowski M, Chruszcz M, Zimmerman MD, Kirillova O, Minor W (2009)
    Benefits of structural genomics for drug discovery research.
    Infect Disord Drug Targets 9: 459-74. [Pub Med ID: 19594422] [Pub Med Central ID: PMC2866842] Times cited: 26
  51. Xu Q, Traag BA, Willemse J, McMullan D, Miller MD, Elsliger MA, Abdubek P, Astakhova T, Axelrod HL, Bakolitsa C, Carlton D, Chen C, Chiu HJ, Chruszcz M, Clayton T, Das D, Deller MC, Duan L, Ellrott K, Ernst D, Farr CL, Feuerhelm J, Grant JC, Grzechnik A, Grzechnik SK, Han GW, Jaroszewski L, Jin KK, Klock HE, Knuth MW, Kozbial P, Krishna SS, Kumar A, Marciano D, Minor W, Mommaas AM, Morse AT, Nigoghossian E, Nopakun A, Okach L, Oommachen S, Paulsen J, Puckett C, Reyes R, Rife CL, Sefcovic N, Tien HJ, Trame CB, van den Bedem H, Wang S, Weekes D, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA, van Wezel GP (2009)
    Structural and functional characterizations of SsgB, a conserved activator of developmental cell division in morphologically complex actinomycetes.
    J. Biol. Chem. 284: 25268-79. [DOI:10.1074/jbc.M109.018564] [Pub Med ID: 19567872] [Pub Med Central ID: PMC2757229] Times cited: 17
  52. Chruszcz M, Chapman MD, Vailes LD, Stura EA, Saint-Remy JM, Minor W, Pomés A (2009)
    Crystal structures of mite allergens Der f 1 and Der p 1 reveal differences in surface-exposed residues that may influence antibody binding.
    J. Mol. Biol. 386: 520-30. [DOI:10.1016/j.jmb.2008.12.049] [Pub Med ID: 19136006] [Pub Med Central ID: PMC2677027] Times cited: 64
  53. Chruszcz M, Borek D, Domagalski M, Otwinowski Z, Minor W (2009)
    X-ray diffraction experiment--the last experiment in the structure elucidation process.
    Adv Protein Chem Struct Biol 77: 23-40. [DOI:10.1016/S1876-1623(09)77002-6] [Pub Med ID: 20663480] [Pub Med Central ID: PMC3128764] Times cited: 6
  54. Artz JD, Dunford JE, Arrowood MJ, Dong A, Chruszcz M, Kavanagh KL, Minor W, Russell RG, Ebetino FH, Oppermann U, Hui R (2008)
    Targeting a uniquely nonspecific prenyl synthase with bisphosphonates to combat cryptosporidiosis.
    Chem. Biol. 15: 1296-306. [DOI:10.1016/j.chembiol.2008.10.017] [Pub Med ID: 19101474] Times cited: 29
  55. Chruszcz M, Zimmerman MD, Wang S, Koclega KD, Zheng H, Evdokimova E, Kudritska M, Cymborowski M, Savchenko A, Edwards A, Minor W (2008)
    Function-biased choice of additives for optimization of protein crystallization - the case of the putative thioesterase PA5185 from Pseudomonas aeruginosa PAO1.
    Cryst Growth Des 8: 4054-4061. [DOI:10.1021/cg800430f] [Pub Med ID: 19898606] [Pub Med Central ID: PMC2700756] Times cited: 3
  56. Minor T, Chruszcz M (2008)
    (S)-(-)-6-(4-Bromo-phen-yl)-2,3,5,6-tetra-hydro-thia-zolo[2,3-b]imidazolium hydrogen oxalate.
    Acta Crystallogr Sect E Struct Rep Online 64: o1954. [DOI:10.1107/S1600536808029085] [Pub Med ID: 21201158] [Pub Med Central ID: PMC2959238] Times cited: 1
  57. Zheng H, Chruszcz M, Lasota P, Lebioda L, Minor W (2008)
    Data mining of metal ion environments present in protein structures.
    J. Inorg. Biochem. 102: 1765-76. [DOI:10.1016/j.jinorgbio.2008.05.006] [Pub Med ID: 18614239] [Pub Med Central ID: PMC2872550] Times cited: 181
  58. Chinigo GM, Paige M, Grindrod S, Hamel E, Dakshanamurthy S, Chruszcz M, Minor W, Brown ML (2008)
    Asymmetric synthesis of 2,3-dihydro-2-arylquinazolin-4-ones: methodology and application to a potent fluorescent tubulin inhibitor with anticancer activity.
    J. Med. Chem. 51: 4620-31. [DOI:10.1021/jm800271c] [Pub Med ID: 18610995] [Pub Med Central ID: PMC2584442] Times cited: 130
  59. Beloglazova N, Brown G, Zimmerman MD, Proudfoot M, Makarova KS, Kudritska M, Kochinyan S, Wang S, Chruszcz M, Minor W, Koonin EV, Edwards AM, Savchenko A, Yakunin AF (2008)
    A novel family of sequence-specific endoribonucleases associated with the clustered regularly interspaced short palindromic repeats.
    J. Biol. Chem. 283: 20361-71. [DOI:10.1074/jbc.M803225200] [Pub Med ID: 18482976] [Pub Med Central ID: PMC2459268] Times cited: 127
  60. Borges AR, Hyacinth M, Lum M, Dingle CM, Hamilton PL, Chruszcz M, Pu L, Sabat M, Caran KL (2008)
    Self-assembled thermoreversible gels of nonpolar liquids by racemic propargylic alcohols with fluorinated and nonfluorinated aromatic rings.
    Langmuir 24: 7421-31. [DOI:10.1021/la800201d] [Pub Med ID: 18553992] Times cited: 22
  61. Chruszcz M, Wlodawer A, Minor W (2008)
    Determination of protein structures--a series of fortunate events.
    Biophys. J. 95: 1-9. [DOI:10.1529/biophysj.108.131789] [Pub Med ID: 18441029] [Pub Med Central ID: PMC2426657] Times cited: 32
  62. Potrzebowski MJ, Potrzebowski WM, Jeziorna A, Ciesielski W, Gajda J, Bujacz GD, Chruszcz M, Minor W (2008)
    Synthesis and solid-state study of supramolecular host-guest assemblies: Bis[6-O,6-O'-(1,2:3,4-diisopropylidene-alpha-D-galactopyranosyl)thiophosphoryl] dichalcogenides.
    J. Org. Chem. 73: 4388-97. [DOI:10.1021/jo8002997] [Pub Med ID: 18507446] Times cited: 7
  63. Slade DJ, Lovelace LL, Chruszcz M, Minor W, Lebioda L, Sodetz JM (2008)
    Crystal structure of the MACPF domain of human complement protein C8 alpha in complex with the C8 gamma subunit.
    J. Mol. Biol. 379: 331-42. [DOI:10.1016/j.jmb.2008.03.061] [Pub Med ID: 18440555] [Pub Med Central ID: PMC2443722] Times cited: 56
  64. Chruszcz M, Potrzebowski W, Zimmerman MD, Grabowski M, Zheng H, Lasota P, Minor W (2008)
    Analysis of solvent content and oligomeric states in protein crystals--does symmetry matter?
    Protein Sci. 17: 623-32. [DOI:10.1110/ps.073360508] [Pub Med ID: 18359856] [Pub Med Central ID: PMC2271157] Times cited: 34
  65. Knapik AA, Minor W, Chruszcz M (2008)
    2,3-Difluoro-benzoic acid.
    Acta Crystallogr Sect E Struct Rep Online 64: o466. [DOI:10.1107/S1600536808001232] [Pub Med ID: 21201492] [Pub Med Central ID: PMC2960366] Times cited: 11
  66. Sasaki T, Maier B, Koclega KD, Chruszcz M, Gluba W, Stukenberg PT, Minor W, Scrable H (2008)
    Phosphorylation regulates SIRT1 function.
    PLoS ONE 3: e4020. [DOI:10.1371/journal.pone.0004020] [Pub Med ID: 19107194] [Pub Med Central ID: PMC2602979] Times cited: 184
  67. Chruszcz M, Kong Y, Dauter Z, Brown ML, Minor W (2007)
    2-amino-4-(4-chloro-3-methylphenyl)-5-propyl-1,3-thiazolium iodide.
    Acta Crystallogr Sect E Struct Rep Online 63: O1598-O1600. [DOI:10.1107/S1600536807009427]
  68. Dobrzycki L, Chruszcz M, Minor W, Wozniak K (2007)
    Stacks of DMANH(+)-scaffolding for ribbon shaped Cl- bridged oxonium ions.
    Crystengcomm 9(2): 152-157. [DOI:10.1039/B614785B] Times cited: 7
  69. Sledz P, Chruszcz M, Minor W (2007)
    Absolute configuration from a redetermination of (+)-5-bromo-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione at 118 (2) K.
    Acta Crystallogr Sect E Struct Rep Online 63: o4159-o4160. [DOI:10.1107/S1600536807046077]
  70. Potrzebowski W, Chruszcz M (2007)
    3,5-Difluorobenzoic acid.
    Acta Crystallogr Sect E Struct Rep Online 63: o2754. [DOI:10.1107/S1600536807019861] Times cited: 8
  71. Raynor JW, Minor W, Chruszcz M (2007)
    Dexamethasone at 119 K.
    Acta Crystallogr Sect E Struct Rep Online 63: o2791-o2793. [DOI:10.1107/S1600536807020806] Times cited: 5
  72. Cymborowski M, Chruszcz M, Dauter Z, Minor W (2007)
    3-Iodo-L-tyrosine hemihydrate.
    Acta Crystallogr Sect E Struct Rep Online 63: O1557-O1559. [DOI:10.1107/S1600536807009129] Times cited: 1
  73. Chruszcz M, Chinigo GM, Capitosti SM, Brown ML, Minor W (2007)
    2-(Biphenyl-4-yl)-2,3-dihydroquinazolin-4(1H)-one.
    Acta Crystallogr Sect E Struct Rep Online 63: O891-O893. [DOI:10.1107/S1600536807002103] Times cited: 2
  74. Koclega KD, Chruszcz M, Minor W (2007)
    3-(1-methylpiperidinio)-1-propanesulfonate.
    Acta Crystallogr Sect E Struct Rep Online 63: O282-O283. [DOI:10.1107/S1600536806052950] Times cited: 1
  75. Raynor JW, Chruszcz M, Minor W (2007)
    N,N,N '',N ''-tetrakis(carboxymethyl)-2,2 ''-(ethylenedioxy)dianilinium dichloride dihydrate.
    Acta Crystallogr Sect E Struct Rep Online 63: o754-o756. [DOI:10.1107/S1600536807001559] Times cited: 1
  76. Dong A, Xu X, Edwards AM, , , Chang C, Chruszcz M, Cuff M, Cymborowski M, Di Leo R, Egorova O, Evdokimova E, Filippova E, Gu J, Guthrie J, Ignatchenko A, Joachimiak A, Klostermann N, Kim Y, Korniyenko Y, Minor W, Que Q, Savchenko A, Skarina T, Tan K, Yakunin A, Yee A, Yim V, Zhang R, Zheng H, Akutsu M, Arrowsmith C, Avvakumov GV, Bochkarev A, Dahlgren LG, Dhe-Paganon S, Dimov S, Dombrovski L, Finerty P, Flodin S, Flores A, Gräslund S, Hammerström M, Herman MD, Hong BS, Hui R, Johansson I, Liu Y, Nilsson M, Nedyalkova L, Nordlund P, Nyman T, Min J, Ouyang H, Park HW, Qi C, Rabeh W, Shen L, Shen Y, Sukumard D, Tempel W, Tong Y, Tresagues L, Vedadi M, Walker JR, Weigelt J, Welin M, Wu H, Xiao T, Zeng H, Zhu H (2007)
    In situ proteolysis for protein crystallization and structure determination.
    Nat. Methods 4: 1019-21. [DOI:10.1038/nmeth1118] [Pub Med ID: 17982461] [Pub Med Central ID: PMC3366506] Times cited: 154
    F1000 Recommended Publication
  77. Koclega KD, Chruszcz M, Zimmerman MD, Cymborowski M, Evdokimova E, Minor W (2007)
    Crystal structure of a transcriptional regulator TM1030 from Thermotoga maritima solved by an unusual MAD experiment.
    J. Struct. Biol. 159: 424-32. [DOI:10.1016/j.jsb.2007.04.012] [Pub Med ID: 17588774] [Pub Med Central ID: PMC2093942] Times cited: 8
  78. Petkowski JJ, Chruszcz M, Zimmerman MD, Zheng H, Skarina T, Onopriyenko O, Cymborowski MT, Koclega KD, Savchenko A, Edwards A, Minor W (2007)
    Crystal structures of TM0549 and NE1324--two orthologs of E. coli AHAS isozyme III small regulatory subunit.
    Protein Sci. 16: 1360-7. [DOI:10.1110/ps.072793807] [Pub Med ID: 17586771] [Pub Med Central ID: PMC2206681] Times cited: 15
  79. Zuo Y, Zheng H, Wang Y, Chruszcz M, Cymborowski M, Skarina T, Savchenko A, Malhotra A, Minor W (2007)
    Crystal structure of RNase T, an exoribonuclease involved in tRNA maturation and end turnover.
    Structure 15: 417-28. [DOI:10.1016/j.str.2007.02.004] [Pub Med ID: 17437714] [Pub Med Central ID: PMC1907377] Times cited: 31
  80. Kirillova O, Chruszcz M, Shumilin IA, Skarina T, Gorodichtchenskaia E, Cymborowski M, Savchenko A, Edwards A, Minor W (2007)
    An extremely SAD case: structure of a putative redox-enzyme maturation protein from Archaeoglobus fulgidus at 3.4 A resolution.
    Acta Crystallogr D Biol Crystallogr. 63: 348-54. [DOI:10.1107/S0907444906055065] [Pub Med ID: 17327672] Times cited: 23
  81. Koclega KD, Chruszcz M, Gawlicka-Chruszcz A, Cymborowski M, Minor W (2007)
    3-(1-Pyridinio)propanesulfonate and 3-(benzyldimethylammonio)propanesulfonate monohydrate.
    Acta Crystallogr C 63: o114-6. [DOI:10.1107/S0108270106054692] [Pub Med ID: 17284802] Times cited: 3
  82. Koclega KD, Chruszcz M, Minor W (2006)
    3-(Ethyldimethylammonio)propanesulfonate.
    Acta Crystallogr Sect E Struct Rep Online 62: O5757-O5759. [DOI:10.1107/S1600536806048069] Times cited: 3
  83. Doyle CR, Zimmerman MD, Chruszcz M, Cymborowski M, Gawlicka-Chruszcz A, Minor W (2006)
    Crystal structure of 6-(4-difluoromethoxy-3-methoxyphenyl)-3(2H)-pyridazinone,C12H10F2N2O3.
    Zeitschrift fur Kristallographie 221: 359-360. [DOI:10.1524/ncrs.2006.0109]
  84. Zimmerman MD, Chruszcz M, Cymborowski M, Zheng HP, Minor W (2006)
    Disodium 4-nitrophenylphosphate hexahydrate.
    Acta Crystallogr Sect E Struct Rep Online 62: M884-M886. [DOI:10.1107/S160053680600941X] Times cited: 1
  85. Segraves EN, Chruszcz M, Neidig ML, Ruddat V, Zhou J, Wecksler AT, Minor W, Solomon EI, Holman TR (2006)
    Kinetic, spectroscopic, and structural investigations of the soybean lipoxygenase-1 first-coordination sphere mutant, Asn694Gly.
    Biochemistry 45: 10233-42. [DOI:10.1021/bi060577e] [Pub Med ID: 16922498] Times cited: 14
  86. Hyacinth M, Chruszcz M, Lee KS, Sabat M, Gao G, Pu L (2006)
    Supramolecular assemblies of chiral propargylic alcohols.
    Angew. Chem. Int. Ed. Engl. 45: 5358-60. [DOI:10.1002/anie.200601594] [Pub Med ID: 16847852] Times cited: 11
  87. Minor W, Cymborowski M, Otwinowski Z, Chruszcz M (2006)
    HKL-3000: the integration of data reduction and structure solution--from diffraction images to an initial model in minutes.
    Acta Crystallogr D Biol Crystallogr. 62: 859-66. [DOI:10.1107/S0907444906019949] [Pub Med ID: 16855301] Times cited: 1,057
  88. Liu Y, Cheney MD, Gaudet JJ, Chruszcz M, Lukasik SM, Sugiyama D, Lary J, Cole J, Dauter Z, Minor W, Speck NA, Bushweller JH (2006)
    The tetramer structure of the Nervy homology two domain, NHR2, is critical for AML1/ETO's activity.
    Cancer Cell 9: 249-60. [DOI:10.1016/j.ccr.2006.03.012] [Pub Med ID: 16616331] Times cited: 85
  89. Dominiak PM, Makal A, Mallinson PR, Trzcinska K, Eilmes J, Grech E, Chruszcz M, Minor W, Woźniak K (2006)
    Continua of interactions between pairs of atoms in molecular crystals.
    Chemistry 12: 1941-9. [DOI:10.1002/chem.200500600] [Pub Med ID: 16389615] Times cited: 59
  90. Chruszcz M, Zheng HP, Cymborowski M, Gawlicka-Chruszcz A, Minor W (2005)
    3-(Morpholinium-1-yl)propanesulfonate.
    Acta Crystallogr Sect E Struct Rep Online 61: O3190-O3191. [DOI:10.1107/S1600536805027728] Times cited: 4
  91. Flanagan JF, Mi LZ, Chruszcz M, Cymborowski M, Clines KL, Kim Y, Minor W, Rastinejad F, Khorasanizadeh S (2005)
    Double chromodomains cooperate to recognize the methylated histone H3 tail.
    Nature 438: 1181-5. [DOI:10.1038/nature04290] [Pub Med ID: 16372014] Times cited: 359
    F1000 Recommended Publication
  92. Chruszcz M, Cymborowski M, Gawlicka-Chruszcz A, Yasukawa S, Ferrara JD, Minor W (2004)
    L-Methioninium chloride and L-selenomethioninium chloride at 103 K.
    Acta Crystallogr C 60: o868-71. [DOI:10.1107/S0108270104025223] [Pub Med ID: 15579969] Times cited: 2
  93. Janda I, Devedjiev Y, Cooper D, Chruszcz M, Derewenda U, Gabrys A, Minor W, Joachimiak A, Derewenda ZS (2004)
    Harvesting the high-hanging fruit: the structure of the YdeN gene product from Bacillus subtilis at 1.8 angstroms resolution.
    Acta Crystallogr D Biol Crystallogr. 60: 1101-7. [DOI:10.1107/S0907444904007188] [Pub Med ID: 15159570] [Pub Med Central ID: PMC2792027] Times cited: 19