Education:
Ph.D. Purdue University (2000) Investigation of Acetate Kinase, Butyrate Kinase, and Caveolin - Miriam Hasson advisor
Faculty Opinions Associate Faculty Member Recommendations

Publications with the Minor Lab

  1. Czub M, Czub MP, Handing KB, Handing K, Venkataramany BS, Cooper DR, Shabalin IG, Minor W (2020)
    Albumin-Based Transport of Nonsteroidal Anti-Inflammatory Drugs in Mammalian Blood Plasma.
    J. Med. Chem. 63: 6847-6862. [DOI:10.1021/acs.jmedchem.0c00225] [Pub Med ID: 32469516]
  2. Bonarek P, Loch JI, Tworzydło M, Cooper DR, Milto K, Wróbel P, Kurpiewska K, Lewiński K (2020)
    Structure-based design approach to rational site-directed mutagenesis of β-lactoglobulin.
    J. Struct. Biol. 210: 107493. [DOI:10.1016/j.jsb.2020.107493] [Pub Med ID: 32169624]
  3. Shabalin IG, Gritsunov A, Hou J, Sławek J, Miks CD, Cooper DR, Minor W, Christendat D (2019)
    Structural and biochemical analysis of Bacillus anthracis prephenate dehydrogenase reveals an unusual mode of inhibition by tyrosine via the ACT domain.
    FEBS J. 287: 2235-2255. [DOI:10.1111/febs.15150] [Pub Med ID: 31750992] [Pub Med Central ID: PMC7239764]
  4. Grabowski M, Cymborowski M, Porebski PJ, Osinski T, Shabalin IG, Cooper D, Cooper DR, Minor W (2019)
    The Integrated Resource for Reproducibility in Macromolecular Crystallography: Experiences of the first four years.
    Struct Dyn 6: 064301. [DOI:10.1063/1.5128672] [Pub Med ID: 31768399] [Pub Med Central ID: PMC6874509]
  5. Lipowska J, Miks CD, Kwon K, Shuvalova L, Zheng H, Lewiński K, Cooper DR, Shabalin IG, Minor W (2019)
    Pyrimidine biosynthesis in pathogens - Structures and analysis of dihydroorotases from Yersinia pestis and Vibrio cholerae.
    Int. J. Biol. Macromol. 136: 1176-1187. [DOI:10.1016/j.ijbiomac.2019.05.149] [Pub Med ID: 31207330] [Pub Med Central ID: PMC6686667] Times cited: 2
  6. Grabowski M, Shabalin I, Porebski PJ, Domagalski MJ, Zheng H, Cooper D, Venkataramany BS, Bourne PE, Minor W (2019)
    Data Sharing in Structural Biology: Advances and Challenges
    in Data Sharing: Recent Progress and Remaining Challenges - Computer Science, Technology and Applications, Nova Science Publishers, New York : 29-68.
  7. Hou J, Zheng H, Tzou WS, Cooper DR, Chruszcz M, Chordia MD, Kwon K, Grabowski M, Minor W (2018)
    Differences in substrate specificity of V. cholerae FabH enzymes suggest new approaches for the development of novel antibiotics and biofuels.
    FEBS J. 285: 2900-2921. [DOI:10.1111/febs.14588] [Pub Med ID: 29917313] [Pub Med Central ID: PMC6105497] Times cited: 1
  8. Porebski PJ, Sroka P, Zheng H, Cooper DR, Minor W (2018)
    Molstack-Interactive visualization tool for presentation, interpretation, and validation of macromolecules and electron density maps.
    Protein Sci. 27: 86-94. [DOI:10.1002/pro.3272] [Pub Med ID: 28815771] [Pub Med Central ID: PMC5734276] Times cited: 15
  9. Zheng H, Cooper DR, Porebski PJ, Shabalin IG, Handing KB, Minor W (2017)
    CheckMyMetal: a macromolecular metal-binding validation tool.
    Acta Crystallogr D Struct Biol 73: 223-233. [DOI:10.1107/S2059798317001061] [Pub Med ID: 28291757] [Pub Med Central ID: PMC5349434] Times cited: 79
  10. Zheng H, Porebski PJ, Grabowski M, Cooper DR, Minor W (2017)
    Databases, Repositories, and Other Data Resources in Structural Biology.
    Methods Mol. Biol. 1607: 643-665. [DOI:10.1007/978-1-4939-7000-1_27] [Pub Med ID: 28573593] [Pub Med Central ID: PMC5587190] Times cited: 1
  11. Grabowski M, Langner KM, Cymborowski M, Porebski PJ, Sroka P, Zheng H, Cooper DR, Zimmerman MD, Elsliger MA, Burley SK, Minor W (2016)
    A public database of macromolecular diffraction experiments.
    Acta Crystallogr D Struct Biol 72: 1181-1193. [DOI:10.1107/S2059798316014716] [Pub Med ID: 27841751] [Pub Med Central ID: PMC5108346] Times cited: 46
  12. Zheng H, Chordia MD, Cooper DR, Chruszcz M, Müller P, Sheldrick GM, Minor W (2014)
    Validation of metal-binding sites in macromolecular structures with the CheckMyMetal web server.
    Nat Protoc 9: 156-70. [DOI:10.1038/nprot.2013.172] [Pub Med ID: 24356774] [Pub Med Central ID: PMC4410975] Times cited: 157
  13. Knapik AA, Petkowski JJ, Otwinowski Z, Cymborowski MT, Cooper DR, Chruszcz M, Krajewska WM, Minor W (2012)
    Structure of Escherichia coli RutC, a member of the YjgF family and putative aminoacrylate peracid reductase of the rut operon.
    Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 68: 1294-9. [DOI:10.1107/S1744309112041796] [Pub Med ID: 23143235] [Pub Med Central ID: PMC3515367] Times cited: 6
  14. Knapik AA, Petkowski JJ, Otwinowski Z, Cymborowski MT, Cooper DR, Majorek KA, Chruszcz M, Krajewska WM, Minor W (2012)
    A multi-faceted analysis of RutD reveals a novel family of α/β hydrolases.
    Proteins 80: 2359-68. [DOI:10.1002/prot.24122] [Pub Med ID: 22641504] [Pub Med Central ID: PMC3459670] Times cited: 5
  15. Shabalin IG, Porebski PJ, Cooper DR, Grabowski M, Onopriyenko O, Grimshaw S, Savchenko A, Chruszcz M, Minor W (2012)
    Structure of anabolic ornithine carbamoyltransferase from Campylobacter jejuni at 2.7 Å resolution.
    Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 68: 1018-24. [DOI:10.1107/S1744309112031259] [Pub Med ID: 22949186] [Pub Med Central ID: PMC3433189] Times cited: 4
  16. Hou J, Wojciechowska K, Zheng H, Chruszcz M, Cooper DR, Cymborowski M, Skarina T, Gordon E, Luo H, Savchenko A, Minor W (2012)
    Structure of a short-chain dehydrogenase/reductase from Bacillus anthracis.
    Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 68: 632-7. [DOI:10.1107/S1744309112017939] [Pub Med ID: 22684058] [Pub Med Central ID: PMC3370898] Times cited: 2
  17. Cooper DR, Porebski PJ, Chruszcz M, Minor W (2011)
    X-ray crystallography: Assessment and validation of protein-small molecule complexes for drug discovery.
    Expert Opin Drug Discov 6: 771-782. [DOI:10.1517/17460441.2011.585154] [Pub Med ID: 21779303] [Pub Med Central ID: PMC3138648] Times cited: 34
  18. Janda I, Devedjiev Y, Cooper D, Chruszcz M, Derewenda U, Gabrys A, Minor W, Joachimiak A, Derewenda ZS (2004)
    Harvesting the high-hanging fruit: the structure of the YdeN gene product from Bacillus subtilis at 1.8 angstroms resolution.
    Acta Crystallogr D Biol Crystallogr. 60: 1101-7. [DOI:10.1107/S0907444904007188] [Pub Med ID: 15159570] [Pub Med Central ID: PMC2792027] Times cited: 20